Pentobarbital will minimize the extent or impact of pimozide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unidentified. Contraindicated (1)pentobarbital will lower the extent or impact of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Women of all ages should not pick estradiol valerate/dienogest ... https://sodium-pentobarbital-use16936.blogrelation.com/27722173/the-2-minute-rule-for-sodium-pentobarbital-euthanasia-dose